I have a 22 250 Lariat, 7.3 18" wheels and 3.55 ratio diff. Absolutely love this truck. Towing a 25', 7000Lb trailer it performs superbly and the ten speed trans is excellent. I got the camper package, which adds rear overload spring and rear sway bar, front springs were already at the max, so no change there. You will definitely feel a stiffer ride than your 150, but you are going from a half ton to 3/4 ton, so that is to be expected. Towing I get 10.5 mpg, 15 mpg empty, of course how hard you push the skinny pedal will affect your numbers.